When can a pyrogenic reaction occur?

A pyrogenic reaction can occur when the body reacts to pyrogens—substances, often produced by bacteria, that can induce fever and other inflammatory responses. In the context of dialysis treatment, these reactions can happen due to various factors, such as bacterial contamination or the presence of endotoxins in the dialysate or equipment.

Since pyrogenic reactions are related to the introduction of these substances into the bloodstream, they can occur throughout the entire duration of the dialysis process. This includes before treatment begins, during the treatment itself, and even after the treatment has been completed. The possibility of such reactions being initiated by contaminated equipment or improper handling emphasizes the importance of strict adherence to infection control and equipment sterilization protocols in dialysis settings. Thus, recognizing that pyrogenic reactions can manifest at multiple points in the dialysis process is essential for ensuring patient safety and effective treatment.