What issue can arise if bicarbonate levels are not properly managed in the body?

When bicarbonate levels in the body are not properly managed, one of the primary concerns is the development of metabolic acidosis. Bicarbonate serves as a crucial buffer in the blood and helps maintain the pH balance within a narrow, healthy range. If bicarbonate levels drop too low, the body cannot adequately neutralize acids, leading to an acidic environment in the blood.

Metabolic acidosis can result from various factors such as kidney dysfunction, where the kidneys are unable to excrete acids effectively, or from excessive production of lactic acid or ketone bodies. When the acid-base balance shifts towards acidosis, it can impair cellular function and lead to systemic complications.

In summary, the proper management of bicarbonate levels is vital for maintaining acid-base homeostasis. If levels are not maintained, it can lead to metabolic acidosis, which poses significant health risks and can affect various organ systems.